Systems biology: Difference between revisions
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==Recent papers== | ==Recent papers== | ||
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/ | ===2006=== | ||
J. | [http://www.cds.caltech.edu/%7Edoyle2/wiki/images/7/74/IEEEProc_Bio.pdf ''Advanced Methods and Algorithms for Biological Networks Analysis''],<br> | ||
H El-Samad , A Papachristodoulou, S Prajna, J Doyle, and M Khammash<br> | |||
In Proc. IEEE, 94 (4): 832-853 APR 2006 (900K) | |||
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/1/1f/PlosCompBio_HS06.pdf ''Module-Based Analysis of Robustness Tradeoffs in the Heat Shock Response System '']<br> | |||
Hiroyuki Kurata, Hana El-Samad, Rei Iwasaki, Hisao Ohtake, John C Doyle, Irina Grigorova, Carol A. Gross, Mustafa Khammash,<br> | |||
[http://compbiol.plosjournals.org/ PLoS Comput Biol] 2(7): July 2006 (1.1MB) | |||
===2005=== | |||
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/9/98/FEBS_PPI05.pdf ''Some protein interaction data do not exhibit power law statistics''],<br> | [http://www.cds.caltech.edu/%7Edoyle2/wiki/images/9/98/FEBS_PPI05.pdf ''Some protein interaction data do not exhibit power law statistics''],<br> | ||
R. Tanaka, T-M Yi, and J. Doyle<br> | R. Tanaka, T-M Yi, and J. Doyle<br> | ||
FEBS letters, 579 (23): 5140-5144 Sept 26 2005 (221K) | FEBS letters, 579 (23): 5140-5144 Sept 26 2005 (221K) | ||
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/f/f2/IEESysBio05.pdf ''Highly optimised global organisation of metabolic networks''],<br> | [http://www.cds.caltech.edu/%7Edoyle2/wiki/images/f/f2/IEESysBio05.pdf ''Highly optimised global organisation of metabolic networks''],<br> | ||
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Proc. Natl. Acad. Sci. USA 102(8): 2736-2741 Feb 22, 2005. (390K) | Proc. Natl. Acad. Sci. USA 102(8): 2736-2741 Feb 22, 2005. (390K) | ||
===2004=== | |||
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/1/13/Cell04.pdf ''Robustness of cellular functions''],<br> | |||
J. Stelling, U. Sauer, Z. Szallasi, F. J. Doyle III, and J. Doyle,<br> | |||
Cell 118: 675–685, Sept 17 2004 (244K) | |||
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/1/ | |||
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/8/82/Trends04.pdf ''Bow ties, metabolism, and disease''],<br> | [http://www.cds.caltech.edu/%7Edoyle2/wiki/images/8/82/Trends04.pdf ''Bow ties, metabolism, and disease''],<br> | ||
Csete M.E. and J.C. Doyle,<br> | Csete M.E. and J.C. Doyle,<br> | ||
Trends in Biotechnology 22(9):446-50 Sept 2004. (121K) | Trends in Biotechnology 22(9):446-50 Sept 2004. (121K) | ||
===2002=== | |||
[http://www.cds.caltech.edu/~doyle2/wiki/skins/common/images/icons/fileicon-pdf.png ''Reverse Engineering of Biological Complexity'']<br> | |||
Csete M and Doyle J,<br> | |||
Science 295 (5560): 1664-1669 Mar 1, 2002. (1.2MB) | |||
==External links== | ==External links== | ||
Revision as of 03:36, 23 February 2008
Biology is the broad study of life, with many fields ...
Systems biology in this research group concerns... :
- their molecular components and biochemistry
- function, structure and interactions of each component or system
- dynamics...
Recent papers
2006
Advanced Methods and Algorithms for Biological Networks Analysis,
H El-Samad , A Papachristodoulou, S Prajna, J Doyle, and M Khammash
In Proc. IEEE, 94 (4): 832-853 APR 2006 (900K)
Module-Based Analysis of Robustness Tradeoffs in the Heat Shock Response System
Hiroyuki Kurata, Hana El-Samad, Rei Iwasaki, Hisao Ohtake, John C Doyle, Irina Grigorova, Carol A. Gross, Mustafa Khammash,
PLoS Comput Biol 2(7): July 2006 (1.1MB)
2005
Some protein interaction data do not exhibit power law statistics,
R. Tanaka, T-M Yi, and J. Doyle
FEBS letters, 579 (23): 5140-5144 Sept 26 2005 (221K)
Highly optimised global organisation of metabolic networks,
R. Tanaka, M. Csete and J. Doyle,
IEE Proc.-Syst. Biol. 152(4): 179, Dec 2005 (820K)
Motifs, control, and stability (including Supplementary Notes: Elementary Feedback Concepts)
Doyle J and Csete M
PLoS Biol 3(11): e392; 2005. (387K)
Surviving Heat Shock: Control Strategies for Robustness and Performance
H. El-Samad, H. Kurata , J.C. Doyle , C.A. Gross, and M. Khammash,
Proc. Natl. Acad. Sci. USA 102(8): 2736-2741 Feb 22, 2005. (390K)
2004
Robustness of cellular functions,
J. Stelling, U. Sauer, Z. Szallasi, F. J. Doyle III, and J. Doyle,
Cell 118: 675–685, Sept 17 2004 (244K)
Bow ties, metabolism, and disease,
Csete M.E. and J.C. Doyle,
Trends in Biotechnology 22(9):446-50 Sept 2004. (121K)
2002
Reverse Engineering of Biological Complexity
Csete M and Doyle J,
Science 295 (5560): 1664-1669 Mar 1, 2002. (1.2MB)
