Systems biology: Difference between revisions

From John C. Doyle
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==Recent papers==
==Recent papers==
Cell.pdf                   22-Jan-2005 18:28  244K
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/1/13/Cell04.pdf ''Robustness of cellular functions''],<br>
J. Stelling, U. Sauer, Z. Szallasi, F. J. Doyle III, and J. Doyle,<br>
Cell 118: 675–685, Sept 17 2004 (244K)


FEBS_PPI.pdf               01-Dec-2005 12:39  221K
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/9/98/FEBS_PPI05.pdf ''Some protein interaction data do not exhibit power law statistics''],<br>
R. Tanaka, T-M Yi, and J. Doyle<br>
FEBS letters, 579 (23): 5140-5144 Sept 26 2005 (221K)


IEEEProc_Bio.pdf           09-Jun-2006 14:12  899K
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/7/74/IEEEProc_Bio.pdf ''Advanced Methods and Algorithms for Biological Networks Analysis''],<br>
H El-Samad , A Papachristodoulou, S Prajna, J Doyle, and M Khammash<br>
In Proc. IEEE, 94 (4): 832-853 APR 2006 (900K)


IEESysBio.pdf               14-Oct-2007 14:17  819K
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/f/f2/IEESysBio05.pdf ''Highly optimised global organisation of metabolic networks''],<br>
R. Tanaka, M. Csete and J. Doyle,<br>
IEE Proc.-Syst. Biol. 152(4): 179, Dec 2005 (820K)


PLOS_Primer.pdf             14-Oct-2007 14:22  386K
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/a/a7/PLOS_Primer05.pdf ''Motifs, control, and stability''] (including ''Supplementary Notes: Elementary Feedback Concepts'')<br>
Doyle J and Csete M<br>
[http://www.plosbiology.org PLoS Biol] 3(11): e392; 2005. (387K)


PNAS_HeatShock.pdf         28-Mar-2005 14:58  390K
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/b/b4/PNAS_HeatShock05.pdf ''Surviving Heat Shock: Control Strategies for Robustness and Performance'']<br>
H. El-Samad, H. Kurata , J.C. Doyle , C.A. Gross, and M. Khammash,<br>
PNAS USA 102(8): 2736-2741 Feb 22, 2005. (390K)


ScienceRevEngBio.pdf       14-Oct-2007 14:19  1.2M
[http://www.cds.caltech.edu/~doyle2/wiki/skins/common/images/icons/fileicon-pdf.png ''Reverse Engineering of Biological Complexity'']<br>
Csete M and Doyle J,<br>
Science 295 (5560): 1664-1669 Mar 1, 2002. (1.2MB)


PlosCompBio_HS.pdf         22-Aug-2006 15:57  1.0M
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/1/1f/PlosCompBio_HS06.pdf ''Module-Based Analysis of Robustness Tradeoffs in the Heat Shock Response System '']<br>
Hiroyuki Kurata, Hana El-Samad, Rei Iwasaki, Hisao Ohtake, John C Doyle, Irina Grigorova, Carol A. Gross, Mustafa Khammash,<br>
[http://compbiol.plosjournals.org/ PLoS Comput Biol] 2(7): July 2006 (1.1MB)


Trends.pdf                 30-Nov-2004 13:10  121K
[http://www.cds.caltech.edu/%7Edoyle2/wiki/images/8/82/Trends04.pdf ''Bow ties, metabolism, and disease''],<br>
Csete M.E. and J.C. Doyle,<br>
Trends in Biotechnology 22(9):446-50 Sept 2004. (121K)


==External links==
==External links==
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[[Category:Research]]
[[Category:Research]]
[[Category:Systems biology]]
[[Category:Systems biology]]
[[Category:Papers by topic]]

Revision as of 05:38, 2 December 2007

Biology is the broad study of life, with many fields ...

Systems biology in this research group concerns... :

- their molecular components and biochemistry

- function, structure and interactions of each component or system

- dynamics...

Recent papers

Robustness of cellular functions,
J. Stelling, U. Sauer, Z. Szallasi, F. J. Doyle III, and J. Doyle,
Cell 118: 675–685, Sept 17 2004 (244K)

Some protein interaction data do not exhibit power law statistics,
R. Tanaka, T-M Yi, and J. Doyle
FEBS letters, 579 (23): 5140-5144 Sept 26 2005 (221K)

Advanced Methods and Algorithms for Biological Networks Analysis,
H El-Samad , A Papachristodoulou, S Prajna, J Doyle, and M Khammash
In Proc. IEEE, 94 (4): 832-853 APR 2006 (900K)

Highly optimised global organisation of metabolic networks,
R. Tanaka, M. Csete and J. Doyle,
IEE Proc.-Syst. Biol. 152(4): 179, Dec 2005 (820K)

Motifs, control, and stability (including Supplementary Notes: Elementary Feedback Concepts)
Doyle J and Csete M
PLoS Biol 3(11): e392; 2005. (387K)

Surviving Heat Shock: Control Strategies for Robustness and Performance
H. El-Samad, H. Kurata , J.C. Doyle , C.A. Gross, and M. Khammash,
PNAS USA 102(8): 2736-2741 Feb 22, 2005. (390K)

Reverse Engineering of Biological Complexity
Csete M and Doyle J,
Science 295 (5560): 1664-1669 Mar 1, 2002. (1.2MB)

Module-Based Analysis of Robustness Tradeoffs in the Heat Shock Response System
Hiroyuki Kurata, Hana El-Samad, Rei Iwasaki, Hisao Ohtake, John C Doyle, Irina Grigorova, Carol A. Gross, Mustafa Khammash,
PLoS Comput Biol 2(7): July 2006 (1.1MB)

Bow ties, metabolism, and disease,
Csete M.E. and J.C. Doyle,
Trends in Biotechnology 22(9):446-50 Sept 2004. (121K)

External links

Additional references